Everything you need to know about Plague Inc.'s deep gameplay systems
Each disease type demands unique strategic approaches and tactical thinking
The most versatile pathogen type. Excellent for beginners with balanced transmission and mutation capabilities.
Rapidly mutating organism that evolves symptoms automatically, requiring careful management to prevent early detection.
Struggles to spread across long distances naturally. Requires strategic use of spore bursts for global reach.
Lives in symbiosis with hosts, generating minimal DNA but remaining hidden from medical detection longer.
Attacks the brain directly with slow progression but extreme difficulty for researchers to identify and cure.
Laboratory-created microscopic machine. Cure research begins immediately, creating an intense race against time.
Engineered to be extremely lethal. The challenge lies in preventing it from eliminating hosts before full infection.
Parasitic brain worm capable of mind control. Can achieve victory through enslavement rather than extinction.
Creates zombie hordes that actively combat humanity's military response. Unique combat-focused gameplay.
Inspired by cinema, this pathogen affects both humans and apes, requiring management of intelligent primate colonies.
Transform into a vampire lord commanding dark powers while spreading your influence across the world.
Community-created content offering unique challenges, historical events, and creative gameplay variations.
The game features a meticulously crafted world model with over 50 nations, each possessing distinct characteristics:
Humanity doesn't simply wait for extinction. The advanced AI creates dynamic, realistic responses:
Various ways to experience the pandemic simulation
Progress through difficulty levels with each pathogen type, unlocking new diseases and genetic modifications.
Reverse the paradigm — coordinate global response to save humanity from an evolving pandemic threat.
Race against the clock to achieve extinction in record time. Compete globally on leaderboards.
Fresh scenarios every day with unique modifiers. Earn rewards and climb the daily rankings.
Experience recreations of real historical pandemics with authentic constraints and objectives.
Themed scenarios based on popular culture, alternative history, and creative what-if situations.
Quick reference guide to help you choose your strategy
| Pathogen | Difficulty | Spread Rate | Stealth | Unique Ability |
|---|---|---|---|---|
| Bacteria | Beginner | Medium | Medium | Bacterial Resilience |
| Virus | Easy | Fast | Low | Viral Instability |
| Fungus | Medium | Slow | High | Spore Burst |
| Parasite | Medium | Medium | Very High | Symbiosis |
| Prion | Hard | Slow | Very High | Neural Atrophy |
| Nano-Virus | Hard | Fast | None | Code Fragments |
| Bio-Weapon | Very Hard | Medium | Low | Gene Compression |
| Neurax Worm | Special | Medium | Medium | Mind Control |
| Necroa Virus | Special | Medium | Low | Zombie Hordes |
Quality-of-life features enhancing the gaming experience
Full save and load functionality lets you experiment with different strategies without losing progress.
In-game guidance system teaches mechanics progressively, making complex systems accessible to newcomers.
Fully localised in English, German, Spanish, Portuguese, Italian, French, Japanese, Korean, and Russian.
Play anywhere without internet connection. Perfect for commutes and travel.
Extensive achievement system with global leaderboards tracking your pandemic performance.
Built from scratch for mobile interfaces with intuitive controls and responsive design.